VISDB Viral Integration Site DataBase

VIS ID

TVIS30014462

Fusion event

HIV-PRDM2 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr1

Cytoband

p36.21

Reference genome

Start

End

14083710/13757384 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-106b-3p ; hsa-mir-541-5p ; hsa-mir-7154-5p ; hsa-mir-203b-3p ; hsa-mir-6854-5p ; hsa-mir-488-3p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-8065 ; hsa-mir-3656 ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-4668-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-542-3p ; hsa-mir-4504 ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-605-5p ; hsa-mir-4668-3p ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-12136/Upstream/1178361; hsa-mir-101-1/Downstream/3101565;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/7421, chr1-CpG: 41/Downstream/135471

Nearest cancer related gene

PRDM2(TSG, No orient, 0)

Upstream sequence

GTTTTTTAAATGACATATTTGTTGGTTTAAGTTTCTAATGAATATTTTCTTTCTCTTAGGTTTTATATTATTTTGGCATTAGTTTTGAAACCAAAAGAGC

Downstream sequence

ACAGTAAGACATTGCTTTTGCCTAACTCCCTCTGCAGTGCAGAGGATCGAGTTTAGGATTATAGAGCTCTTTCATTTTGTCTTATTGATGAGAAGCTTTA

Target sequence

AAACACCCCAAATAGTTTTTAAAAACACAGATTGCATTTTTACTGCTTTCTAGCTATTGTCTTTCAAGTGTTTTTTAAATGACATATTTGTTGGTTTAAGTTTCTAATGAATATTTTCTTTCTCTTAGGTTTTATATTATTTTGGCATTAGTTTTGAAACCAAAAGAGC