Basic Information
VIS ID
TVIS30014467
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.13
Reference genome
GRCh37/hg19
Start
18821331/18494837 (Hg38)
End
18821650/18494837 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/1216862; hsa-mir-101-1/Downstream/388365;
Nearest TSS
ENST00000473358/Upstream/13855; ENST00000400661/Downstream/136169;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/11664, chr1-CpG: 201/Downstream/135564
Nearby gene
KLHDC7A(No orient, 8851)
Upstream sequence
gtttcttgactgggcttacgggttttaggaggaagaccacagaggtaaagtgcccttctcctcatatgatattaagagtgcatgctactaacacaactta
Downstream sequence
tactgcaatactacattgtttaattccttaatcagattatctagtttgggccatgaggagctctttcagttggcacctctgtccttttggtacaccctca
Target sequence
ttactgttgatgcggaccttgatcacctggctgaggtggtgtttgccacatttctctgctgtgaacctattcttttttccccttgccatactctaccctagagaaggaagtcactgtttgcagcttatagggtgaagtgtcatgttctgcctccttgatgcagggagtatctacaaaaattatttggaactcgtctctgtggcagattcatctattcttccttatttatttacttattcaatcatctatttatat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate