Basic Information
VIS ID
TVIS30014483
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
26808998/26482507 (Hg38)
End
26808833/26482507 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/576053; hsa-mir-101-1/Downstream/72035;
Nearest TSS
ENST00000473358/Upstream/9078; ENST00000525525/Downstream/47254;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/9156, chr1-CpG: 125/Downstream/17678
Nearby gene
HMGN2(No orient, 5865)
Upstream sequence
gtttccatattagatacttataatatccgtaatcccttcattctgtgtgtgtgtgttttgttttgttttgtttttgagataagagtccggctctgtcacc
Downstream sequence
cagcctggagttcagtggcatgaacactgctcactgcagcttcagtctctgagctcaggtgatactcccacttcagcctcctgaatagctgggattacag
Target sequence
tagcctcccaaagtgctggggattagtggcatgagccaccacaccaagccTgagttctttatatagtttccatattagatacttataatatccgtaatcccttcattctgtgtgtgtgtgttttgttttgttttgtttttgagataagagtccggctctgtcacc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate