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TVIS30014489
Basic Information
VIS ID
TVIS30014489
Fusion event
HIV-WASF2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
27772803/27446290 (Hg38)
End
27772769/27446290 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
WASF2
miRNAs that regulate target gene
hsa-mir-146a-5p
;
hsa-mir-124-3p
;
hsa-mir-1-3p
;
hsa-mir-34a-5p
;
hsa-mir-7-5p
;
hsa-mir-26b-5p
;
hsa-mir-1224-5p
;
hsa-mir-940
;
hsa-mir-877-3p
;
hsa-mir-425-5p
;
hsa-mir-1238-3p
;
hsa-mir-670-3p
;
hsa-mir-4713-5p
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-627-3p
;
hsa-mir-5003-3p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-629-3p
;
hsa-mir-5089-5p
;
hsa-mir-6728-5p
;
hsa-mir-769-3p
;
hsa-mir-450b-3p
;
hsa-mir-4279
;
hsa-mir-876-5p
;
hsa-mir-3167
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-195-3p
;
hsa-mir-16-2-3p
;
hsa-mir-1343-5p
;
hsa-mir-143-5p
;
hsa-mir-1827
;
hsa-mir-1910-3p
;
hsa-mir-1914-3p
;
hsa-mir-197-3p
;
hsa-mir-214-3p
;
hsa-mir-3173-3p
;
hsa-mir-3184-5p
;
hsa-mir-3610
;
hsa-mir-3612
;
hsa-mir-3619-5p
;
hsa-mir-3944-5p
;
hsa-mir-412-3p
;
hsa-mir-423-5p
;
hsa-mir-4261
;
hsa-mir-4300
;
hsa-mir-4424
;
hsa-mir-4487
;
hsa-mir-4514
;
hsa-mir-4690-5p
;
hsa-mir-4692
;
hsa-mir-4695-5p
;
hsa-mir-5188
;
hsa-mir-5194
;
hsa-mir-541-3p
;
hsa-mir-5582-5p
;
hsa-mir-5591-5p
;
hsa-mir-6072
;
hsa-mir-6499-3p
;
hsa-mir-650
;
hsa-mir-6511a-5p
;
hsa-mir-654-5p
;
hsa-mir-6721-5p
;
hsa-mir-6726-5p
;
hsa-mir-6728-3p
;
hsa-mir-6734-5p
;
hsa-mir-6738-5p
;
hsa-mir-6754-3p
;
hsa-mir-6891-3p
;
hsa-mir-6891-5p
;
hsa-mir-761
;
hsa-mir-875-3p
;
hsa-mir-920
;
hsa-mir-939-5p
;
hsa-mir-96-3p
;
hsa-mir-1276
;
hsa-mir-1910-5p
;
hsa-mir-216b-3p
;
hsa-mir-24-3p
;
hsa-mir-3120-3p
;
hsa-mir-3155a
;
hsa-mir-3155b
;
hsa-mir-3614-5p
;
hsa-mir-3677-5p
;
hsa-mir-4264
;
hsa-mir-4286
;
hsa-mir-4304
;
hsa-mir-4311
;
hsa-mir-4438
;
hsa-mir-451b
;
hsa-mir-455-3p
;
hsa-mir-4696
;
hsa-mir-484
;
hsa-mir-5095
;
hsa-mir-583
;
hsa-mir-626
;
hsa-mir-6873-5p
;
hsa-mir-6876-3p
;
hsa-mir-7151-3p
;
hsa-mir-8064
;
hsa-mir-9500
;
hsa-mir-1304-3p
;
hsa-mir-1307-3p
;
hsa-mir-3615
;
hsa-mir-4284
;
hsa-mir-4512
;
hsa-mir-4638-5p
;
hsa-mir-4757-5p
;
hsa-mir-505-5p
;
hsa-mir-6741-3p
;
hsa-mir-6744-3p
Nearest miRNA
hsa-mir-12136/Upstream/891697; hsa-mir-101-1/Downstream/3292866;
Nearest TSS
ENST00000473358/Upstream/53646;
ENST00000492975/Downstream/10908;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/53445
,
chr1-CpG: 55/Downstream/43541
Upstream sequence
ATATTTTAAATTAACCTTTGACATTAGAAAAATGCAAGAAACTGGTATCTCTTTCAATATATATATAAAGCTGTTCTTTATGGATCTTTGTTGTGATTTC
Downstream sequence
ACCCACAAACAATTTTACAGGGACCGCAAAGAGGGGCAATTAAATACCACCTGCCCAAACTGAACTGGTATTTCTTGTCTGCTATAAATCATGTTAAAGG
Target sequence
AAAGCTGTTCTTTATGGATCTTTGTTGTGATTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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