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TVIS30014491
Basic Information
VIS ID
TVIS30014491
Fusion event
HIV-PHACTR4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
GRCh37/hg19
Start
28795546/28469035 (Hg38)
End
28795255/28469035 (Hg38)
Orient
-
Location type
Intronic
Target gene
PHACTR4
miRNAs that regulate target gene
hsa-mir-361-5p
;
hsa-mir-98-5p
;
hsa-mir-877-3p
;
hsa-mir-484
;
hsa-mir-92a-3p
;
hsa-mir-181a-5p
;
hsa-mir-222-3p
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-769-5p
;
hsa-mir-4786-5p
;
hsa-mir-5695
;
hsa-mir-454-5p
;
hsa-mir-665
;
hsa-mir-887-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-7160-5p
;
hsa-mir-202-3p
;
hsa-mir-4500
;
hsa-mir-4458
;
hsa-let-7i-5p
;
hsa-let-7g-5p
;
hsa-let-7f-5p
;
hsa-let-7e-5p
;
hsa-let-7d-5p
;
hsa-let-7c-5p
;
hsa-let-7b-5p
;
hsa-let-7a-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-7162-3p
;
hsa-mir-1281
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-6888-5p
;
hsa-mir-1294
;
hsa-mir-22-3p
;
hsa-mir-2278
;
hsa-mir-3065-3p
;
hsa-mir-3180-3p
;
hsa-mir-3180
;
hsa-mir-3184-5p
;
hsa-mir-3190-3p
;
hsa-mir-3196
;
hsa-mir-3617-3p
;
hsa-mir-3656
;
hsa-mir-383-3p
;
hsa-mir-3976
;
hsa-mir-423-5p
;
hsa-mir-4459
;
hsa-mir-4710
;
hsa-mir-4722-5p
;
hsa-mir-6079
;
hsa-mir-6134
;
hsa-mir-6165
;
hsa-mir-671-5p
;
hsa-mir-6816-5p
;
hsa-mir-6828-5p
;
hsa-mir-6894-5p
;
hsa-mir-7854-3p
Nearest miRNA
hsa-mir-12136/Upstream/1914442; hsa-mir-101-1/Downstream/2270121;
Nearest TSS
ENST00000473358/Upstream/30864;
ENST00000632964/Downstream/22660;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/98815
,
chr1-CpG: 78/Downstream/49106
Nearest cancer related gene
PHACTR4
(TSG, No orient, 0)
Upstream sequence
ccctggactaaacTGCAGAGCTCATTCTTAGCTTGAGGTAAATAGCCCAAAACAATAGACCTTGTAACTGAGgaatcagtattagtccatgaggggtcct
Downstream sequence
caacaaaagaagaaaaatagaacagttcacagagcatttcttagagctaaatagatttaatttaaaggactctcttttattctaaaattacaaccttcct
Target sequence
gacactacccgtagagtttctgattttagtaagcctgggatgggcttgagaatttgcctttctaataggttcccagatgacactgatgctgctctccagggagcacacattaagagcctctgCTCTACACCAGTGGCATACCacccttttcaagttaaggcaacatataaaatgataatttgtgtatgataccctggactaaacTGCAGAGCTCATTCTTAGCTTGAGGTAAATAGCCCAAAACAATAGACCTTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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