Basic Information
VIS ID
TVIS30014491
Fusion event
HIV-PHACTR4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
End
28795255/28469035 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/1914442; hsa-mir-101-1/Downstream/2270121;
Nearest cancer related gene
PHACTR4(TSG, No orient, 0)
Upstream sequence
ccctggactaaacTGCAGAGCTCATTCTTAGCTTGAGGTAAATAGCCCAAAACAATAGACCTTGTAACTGAGgaatcagtattagtccatgaggggtcct
Downstream sequence
caacaaaagaagaaaaatagaacagttcacagagcatttcttagagctaaatagatttaatttaaaggactctcttttattctaaaattacaaccttcct
Target sequence
gacactacccgtagagtttctgattttagtaagcctgggatgggcttgagaatttgcctttctaataggttcccagatgacactgatgctgctctccagggagcacacattaagagcctctgCTCTACACCAGTGGCATACCacccttttcaagttaaggcaacatataaaatgataatttgtgtatgataccctggactaaacTGCAGAGCTCATTCTTAGCTTGAGGTAAATAGCCCAAAACAATAGACCTTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate