Basic Information
VIS ID
TVIS30014492
Fusion event
HIV-YTHDF2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
GRCh37/hg19
Start
29071157/28744645 (Hg38)
End
29071279/28744645 (Hg38)
Orient
+
Location type
Intronic
Target gene
YTHDF2
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-615-3p ; hsa-mir-106b-5p
Nearest miRNA
hsa-mir-12136/Upstream/2190052; hsa-mir-101-1/Downstream/1994511;
Nearest TSS
ENST00000473358/Upstream/5554; ENST00000621425/Downstream/67497;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/6842, chr1-CpG: 26/Downstream/30633
Upstream sequence
TCAAACTAGAGTTGAATTTGAAAGAGTTGGTAGCGTTTGCTCTGTGAGTATTGAGTGAATGTAAACTTTAGGATTATAAGAGGATGATAAAACTGGTTGG
Downstream sequence
aagtgatccccccatctcagcttcgtgactagctgggatcacagtcatgcaccaccatgcccggctagtttttcatgttttttgtagagctgggttttgc
Target sequence
AGCAGATAATGATATATTATCTGGGATTTATACTTACttttttttggacagggttctctgttgcccaggctggagtgcagtggcatgatgtccgcccactccagcctccaccttctgggctc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate