Basic Information
VIS ID
TVIS30014493
Fusion event
HIV-PUM1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p35.2
Reference genome
GRCh37/hg19
Start
31456828/30983981 (Hg38)
End
31456892/30983981 (Hg38)
Orient
+
Location type
Intronic
Target gene
PUM1
miRNAs that regulate target gene
hsa-mir-423-3p ; hsa-mir-151a-3p ; hsa-mir-181a-5p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-296-3p ; hsa-mir-324-3p ; hsa-mir-324-5p ; hsa-mir-186-5p ; hsa-mir-99a-5p ; hsa-mir-568 ; hsa-mir-508-3p ; hsa-mir-219a-5p ; hsa-mir-4445-5p ; hsa-mir-4782-3p ; hsa-mir-6766-3p ; hsa-mir-142-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-340-5p ; hsa-mir-6809-5p ; hsa-mir-7112-5p ; hsa-mir-4708-3p ; hsa-mir-651-3p ; hsa-mir-99b-3p ; hsa-mir-99a-3p ; hsa-mir-335-3p ; hsa-mir-4528 ; hsa-mir-4283 ; hsa-mir-760 ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-3149 ; hsa-mir-5004-3p ; hsa-mir-3618 ; hsa-mir-4696 ; hsa-mir-571 ; hsa-mir-451b ; hsa-mir-4704-5p ; hsa-mir-548e-5p
Nearest miRNA
hsa-mir-12136/Upstream/244749; hsa-mir-101-1/Downstream/774679;
Nearest TSS
ENST00000473358/Upstream/1836; ENST00000479629/Downstream/11078;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/74862, chr1-CpG: 60/Downstream/81584
Upstream sequence
cgtgagccaccacacctggGCTATATATTTTTTTAATATTACATGTAAGTCATTTTATGTATGTGTACTGTATCTGTAAATATACACGGAAATACATGGC
Downstream sequence
TAAAACATTCTGAAAGCAGGAACTATTACTTTTAACTAAAAGCAAACAAGCCTTACAAGAGACCCCATATAGCCTATGTTTGAGAGCTGATTAATATCTT
Target sequence
ATGTGGGAATACCACAAAAGTAATCATTCCATATAACATTAGCTTGTGGTTTTCACCACCACAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate