Basic Information
VIS ID
TVIS30014494
Fusion event
HIV-KHDRBS1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p35.2
Reference genome
GRCh37/hg19
Start
32523872/32058271 (Hg38)
End
32523962/32058271 (Hg38)
Orient
+
Location type
Intronic
Target gene
KHDRBS1
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-27b-3p ; hsa-mir-34a-5p ; hsa-mir-92a-3p ; hsa-mir-203a-3p ; hsa-mir-204-3p
Nearest miRNA
hsa-mir-12136/Upstream/299536; hsa-mir-101-1/Downstream/28678;
Nearest TSS
ENST00000473358/Upstream/44089; ENST00000466321/Downstream/13760;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/43289, chr1-CpG: 80/Downstream/14333
Nearby gene
KHDRBS1(No orient, 14400)
Upstream sequence
ctacctcctgggctcaagacatcctctcacctcagcctccagagtagctgggactgtaggcatgggccactgcacccagcttatttttttattttttgta
Downstream sequence
agtgctacgattacaggtgtgagccactgcacctggcTGACCTTAAAAAAGCAAAGTTTATCATAGAGTTTTGGTTTCCAATTCACAGGGTGGTTGAAAG
Target sequence
gagacaaggtattactatgttgcccaggatggagaacttctggcctcaagcaatctggcctcaagcaatcctcccatctcggcatcccaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate