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TVIS30014509
Basic Information
VIS ID
TVIS30014509
Fusion event
HIV-MEAF6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37/hg19
Start
37963910/37498309 (Hg38)
End
37963546/37498309 (Hg38)
Orient
-
Location type
Intronic
Target gene
MEAF6
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-10a-5p
;
hsa-mir-5011-5p
;
hsa-mir-410-3p
;
hsa-mir-3163
;
hsa-mir-1277-5p
;
hsa-mir-5692a
;
hsa-mir-5698
;
hsa-mir-183-5p
;
hsa-mir-891a-3p
;
hsa-mir-143-5p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-6499-3p
;
hsa-mir-6787-3p
;
hsa-mir-5693
;
hsa-mir-1285-5p
;
hsa-mir-4665-3p
;
hsa-mir-378a-5p
;
hsa-mir-4454
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-7107-5p
;
hsa-mir-1234-3p
;
hsa-mir-5096
;
hsa-mir-1248
;
hsa-mir-5088-3p
;
hsa-mir-4289
;
hsa-mir-6866-3p
;
hsa-mir-188-5p
;
hsa-mir-382-3p
;
hsa-mir-5572
;
hsa-mir-4260
;
hsa-mir-450a-2-3p
;
hsa-mir-6803-5p
;
hsa-mir-7109-5p
;
hsa-mir-6751-5p
;
hsa-mir-4665-5p
;
hsa-mir-1275
;
hsa-mir-3972
;
hsa-mir-1202
;
hsa-mir-6864-5p
;
hsa-mir-6126
;
hsa-mir-127-5p
;
hsa-mir-526b-5p
;
hsa-mir-138-5p
;
hsa-mir-3194-5p
;
hsa-mir-7515
;
hsa-mir-3179
;
hsa-mir-6806-3p
;
hsa-mir-3928-5p
;
hsa-mir-4635
;
hsa-mir-548q
;
hsa-mir-4328
;
hsa-mir-1245b-3p
;
hsa-mir-575
;
hsa-mir-4676-5p
;
hsa-mir-5683
;
hsa-mir-320e
;
hsa-mir-1294
;
hsa-mir-3154
;
hsa-mir-3919
;
hsa-mir-4316
;
hsa-mir-4756-3p
;
hsa-mir-5088-5p
;
hsa-mir-6132
;
hsa-mir-6510-5p
;
hsa-mir-6770-5p
;
hsa-mir-6801-5p
;
hsa-mir-6822-3p
;
hsa-mir-6828-5p
;
hsa-mir-6836-5p
;
hsa-mir-6844
;
hsa-mir-758-3p
;
hsa-mir-9500
Nearest miRNA
hsa-mir-12136/Upstream/18020; hsa-mir-101-1/Downstream/2626;
Nearest TSS
ENST00000473358/Upstream/16619;
ENST00000490312/Downstream/15211;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/23689
,
chr1-CpG: 71/Downstream/16002
Upstream sequence
CAAAATAGTTTCACTTTAGACATTTGGGAGAGTATACAGTAGGTGTATGAAACTAGGAATTATCAAATATTTCACTTTCAGCCTGACTTGACTTTGTTCA
Downstream sequence
CAAATCAAAATAGACTGTATCTAGTTAATCAAAACTTTACAGACTATCTAAAGTAATTTTTTATAGTAACAGAAACTTATAAGAGTAGCTATGTTATTTT
Target sequence
CAGGGATCTGGAAGGAGCAGTACAGAGAAGGAGACCATTTTGTGCCATCACCACTAGCAGGCCATGATCTGGGCAGGCCTCCAAAGCAAACATTAACCTGGAGCATGACACCTGCTCCTTCACCGGCTCCAACACCTTCCAGACTAAAACAATAAGCAAATGGCTACATTTAGGTGCTAAAACAATATGCAAATGGCTACATTTCCTCCTAGACAATGTTTGCAAGAGTAAAGCTGGAAGAAAGCTTAATGTCAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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