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TVIS30014515
Basic Information
VIS ID
TVIS30014515
Fusion event
HIV-HIVEP3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.2
Reference genome
GRCh37/hg19
Start
42361213/41895542 (Hg38)
End
42361292/41895542 (Hg38)
Orient
+
Location type
Intronic
Target gene
HIVEP3
miRNAs that regulate target gene
hsa-mir-10a-5p
;
hsa-mir-26b-5p
;
hsa-mir-218-5p
;
hsa-mir-149-3p
;
hsa-mir-6795-5p
;
hsa-mir-6887-5p
;
hsa-mir-625-5p
;
hsa-mir-486-3p
;
hsa-mir-6721-5p
;
hsa-mir-92b-5p
;
hsa-mir-4763-3p
;
hsa-mir-1207-5p
;
hsa-mir-4524a-3p
;
hsa-mir-211-3p
;
hsa-mir-6743-5p
;
hsa-mir-4688
;
hsa-mir-4524b-3p
;
hsa-mir-6079
;
hsa-mir-3118
;
hsa-mir-134-5p
;
hsa-mir-920
;
hsa-mir-6726-5p
;
hsa-mir-5591-5p
;
hsa-mir-4300
;
hsa-mir-6090
;
hsa-mir-6081
;
hsa-mir-3192-5p
;
hsa-mir-4538
;
hsa-mir-4453
;
hsa-mir-100-3p
;
hsa-mir-6827-5p
;
hsa-mir-4753-3p
;
hsa-mir-6873-3p
;
hsa-mir-7111-3p
;
hsa-mir-130b-5p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-5196-3p
;
hsa-mir-3183
;
hsa-mir-3591-3p
;
hsa-mir-21-3p
;
hsa-mir-6868-3p
;
hsa-mir-505-5p
;
hsa-mir-4290
;
hsa-mir-3194-5p
;
hsa-mir-1237-3p
;
hsa-mir-1248
;
hsa-mir-660-3p
;
hsa-mir-5193
;
hsa-mir-4687-5p
;
hsa-mir-4667-3p
;
hsa-mir-6858-3p
;
hsa-mir-4494
;
hsa-mir-499b-5p
;
hsa-mir-5586-5p
;
hsa-mir-665
;
hsa-mir-145-3p
;
hsa-mir-2355-5p
;
hsa-mir-4794
;
hsa-mir-5580-5p
;
hsa-mir-652-5p
;
hsa-mir-664a-5p
;
hsa-mir-6732-3p
Nearest miRNA
hsa-mir-12136/Upstream/1138170; hsa-mir-101-1/Downstream/1276110;
Nearest TSS
ENST00000473358/Upstream/25912;
ENST00000372581/Downstream/22956;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/232581
,
chr1-CpG: 38/Downstream/22427
Nearest cancer related gene
HIVEP3
(TSG, No orient, 0)
Upstream sequence
CTAACATTACCAGAGGCAAAGGTGCTTAGGTTAACCAAAAAGCAGGACCAGACTGTTGGCAACCCAGTGTGCTAATGCAGGCCACCCAGGCCAATCAGAA
Downstream sequence
TAGAGGTGTAACTGGACCCCCCGCAGGCCCAAGGGAAGGCTGTTCTAGCTAACGGTAAGGAGAGGAGTAGAAGGCAAGGTGGAGGAGGGCCTTCTGAGGC
Target sequence
GTACTGACCAGAGAAAGGCACATTTCAGACTAAATAAATATTTATCTTTTTTGAAATTACTTAAAGATTGCAATTTGTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT4
Sample type
PBMC
Age
39
Gender
Male
CpG Island Information
×
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