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TVIS30014516
Basic Information
VIS ID
TVIS30014516
Fusion event
HIV-FOXJ3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.2
Reference genome
GRCh37/hg19
Start
42724513/42258842 (Hg38)
End
42724737/42258842 (Hg38)
Orient
+
Location type
Intronic
Target gene
FOXJ3
miRNAs that regulate target gene
hsa-mir-122-5p
;
hsa-mir-130b-3p
;
hsa-mir-196a-5p
;
hsa-mir-93-5p
;
hsa-mir-197-3p
;
hsa-mir-20a-5p
;
hsa-let-7a-5p
;
hsa-mir-494-3p
;
hsa-mir-3908
;
hsa-mir-17-5p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-3609
;
hsa-mir-548ah-5p
;
hsa-mir-4796-3p
;
hsa-mir-3675-3p
;
hsa-mir-4684-5p
;
hsa-mir-27a-3p
;
hsa-mir-27b-3p
;
hsa-mir-513a-5p
;
hsa-mir-5089-3p
;
hsa-mir-5589-3p
;
hsa-mir-5585-3p
;
hsa-mir-6800-5p
;
hsa-mir-610
;
hsa-mir-3117-5p
;
hsa-mir-95-5p
;
hsa-mir-425-5p
;
hsa-mir-1179
;
hsa-mir-4703-5p
;
hsa-mir-3942-5p
;
hsa-mir-376c-3p
;
hsa-mir-3662
;
hsa-mir-708-5p
;
hsa-mir-3139
;
hsa-mir-28-5p
;
hsa-mir-377-3p
;
hsa-mir-8064
;
hsa-mir-342-3p
;
hsa-mir-4639-3p
;
hsa-mir-335-3p
;
hsa-mir-1305
;
hsa-mir-498
;
hsa-mir-6802-3p
;
hsa-mir-3157-5p
;
hsa-mir-4691-3p
;
hsa-mir-6771-3p
;
hsa-mir-548c-3p
;
hsa-mir-1285-3p
;
hsa-mir-31-5p
;
hsa-mir-3187-5p
;
hsa-mir-371a-5p
;
hsa-mir-371b-5p
;
hsa-mir-372-5p
;
hsa-mir-373-5p
;
hsa-mir-4432
;
hsa-mir-4696
;
hsa-mir-508-5p
;
hsa-mir-5189-5p
;
hsa-mir-612
;
hsa-mir-616-5p
;
hsa-mir-6512-3p
;
hsa-mir-661
;
hsa-mir-6720-5p
;
hsa-mir-6849-3p
;
hsa-mir-6860
;
hsa-mir-766-3p
;
hsa-mir-939-3p
Nearest miRNA
hsa-mir-12136/Upstream/1501470; hsa-mir-101-1/Downstream/912810;
Nearest TSS
ENST00000473358/Upstream/52831;
ENST00000410070/Downstream/19745;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/112822
,
chr1-CpG: 102/Downstream/75752
Upstream sequence
ACATCCTATTAAGGGATTAACAGACATATCTTGCTTTTAAATCATAGTGCCAATCAATCCTTTTAGAAACTTTAAGTTAGAGATAAAGTTTTACTATATC
Downstream sequence
aatgaaacaaaactgctgatatgcacaacgacatggatagctctcaaatacattatactaaagcaaaaaagccagactcagaaggccatgtactatatga
Target sequence
ATAACGAATTCCCAAGAAACAGATGGCTCACCTACATAATCCACTCACAAGGCAGCTTAACTTGACTATTATGTTACTACTTGAGTGTTATAGCTCAATATCTGTCAAGTCTAAGCCGAAAAGAAAGTAACTTGATGGTCAAATGATCATACAACTAACAAAAACatgtctttcaaatagtgattaaactctgataaatccgtgtgatggaatatatgcaatga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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