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TVIS30014519
Basic Information
VIS ID
TVIS30014519
Fusion event
HIV-PTPRF integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.2
Reference genome
GRCh37/hg19
Start
44034729/43569058 (Hg38)
End
44034585/43569058 (Hg38)
Orient
-
Location type
Intronic
Target gene
PTPRF
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-24-3p
;
hsa-mir-1914-5p
;
hsa-mir-1229-3p
;
hsa-mir-744-5p
;
hsa-mir-455-3p
;
hsa-mir-15b-3p
;
hsa-mir-221-3p
;
hsa-mir-1260b
;
hsa-mir-4665-5p
;
hsa-mir-1275
;
hsa-mir-4662a-5p
;
hsa-mir-4472
;
hsa-mir-4447
;
hsa-mir-3190-3p
;
hsa-mir-5010-5p
;
hsa-mir-4525
;
hsa-mir-6870-5p
;
hsa-mir-7111-5p
;
hsa-mir-5698
;
hsa-mir-4723-5p
;
hsa-mir-625-5p
;
hsa-mir-3175
;
hsa-mir-6878-5p
;
hsa-mir-4795-5p
;
hsa-mir-1296-3p
;
hsa-mir-575
;
hsa-mir-6858-3p
;
hsa-mir-4676-5p
;
hsa-mir-6516-5p
;
hsa-mir-1273e
;
hsa-mir-6885-5p
;
hsa-mir-328-5p
;
hsa-mir-486-3p
;
hsa-mir-6499-3p
;
hsa-mir-2467-3p
;
hsa-mir-298
;
hsa-mir-6086
;
hsa-mir-377-5p
;
hsa-mir-4537
;
hsa-mir-219b-3p
;
hsa-mir-4532
;
hsa-mir-4257
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-302f
;
hsa-mir-3714
;
hsa-mir-4484
;
hsa-mir-6768-3p
;
hsa-mir-548an
;
hsa-mir-4730
;
hsa-mir-608
;
hsa-mir-4651
;
hsa-mir-6842-5p
;
hsa-mir-7110-5p
;
hsa-mir-6752-5p
;
hsa-mir-25-5p
;
hsa-mir-658
;
hsa-mir-4787-5p
;
hsa-mir-493-5p
;
hsa-let-7g-3p
;
hsa-let-7a-2-3p
;
hsa-let-7c-3p
;
hsa-mir-542-3p
;
hsa-mir-4504
;
hsa-mir-2115-5p
;
hsa-mir-4679
;
hsa-mir-4677-3p
;
hsa-mir-4684-5p
;
hsa-mir-1268b
;
hsa-mir-1268a
;
hsa-mir-585-3p
;
hsa-mir-4486
;
hsa-mir-939-3p
;
hsa-mir-6827-3p
;
hsa-mir-340-3p
;
hsa-mir-7851-3p
;
hsa-mir-619-3p
;
hsa-mir-6771-3p
;
hsa-mir-425-3p
;
hsa-mir-3157-5p
;
hsa-mir-7106-3p
;
hsa-mir-4660
;
hsa-mir-4655-3p
;
hsa-mir-4469
;
hsa-mir-6803-3p
;
hsa-mir-4530
;
hsa-mir-6736-3p
;
hsa-mir-4691-3p
;
hsa-mir-646
Nearest miRNA
hsa-mir-12136/Upstream/120447; hsa-mir-101-1/Downstream/269564;
Nearest TSS
ENST00000473358/Upstream/23982;
ENST00000467464/Downstream/13422;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/2891
,
chr1-CpG: 44/Downstream/22026
Upstream sequence
AGGGAGAAAGCTCAAGGTCAAGGCTGCAGTAACGAATAGGTCAAGGTCAGGATCGGAGTTAGAAGGGGATCATTGGTAGGGCTGGGGGTGCCCCGGGTCA
Downstream sequence
GGGCTAGAGACCAGGCGGTGACCTGGGGCTCTGCCATGTGATAGAGCTGAAGGCTGGATGAAGGGAACACTGTGTGTGCGGACAGGGGAGAGGGGGCTGG
Target sequence
TGGTCTGCAGCCCTGACCGTGACTCCCAGGGTCAGGACTAAGTGAGGGAGAAAGCTCAAGGTCAAGGCTGCAGTAACGAATAGGTCAAGGTCAGGATCGGAGTTAGAAGGGGATCATTGGTAGGGCTGGGGGTGCCCCGGGTCA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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