Basic Information
VIS ID
TVIS30014520
Fusion event
HIV-FAF1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
51305870/50840198 (Hg38)
End
51305847/50840198 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
FAF1
miRNAs that regulate target gene
hsa-mir-146a-5p ; hsa-mir-24-3p ; hsa-mir-26b-5p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-12136/Upstream/6294646; hsa-mir-101-1/Downstream/219639;
Nearest TSS
ENST00000473358/Upstream/134147; ENST00000371761/Downstream/119540;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/412125, chr1-CpG: 65/Downstream/119577
Upstream sequence
aaaattacctcaaaatgtatcatataccttaacataaaagctaaaaactgtaaaatttctagaagaaaacataggaaaaaatctttatggccttggttaa
Downstream sequence
ggaaaggatttcccacagaggatacgaaagcataaacaataaaataattcataaattgaattttattcaagttaaaacctttgactgtcaaaagacccca
Target sequence
aaaatctttatggccttggttaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate