Basic Information
VIS ID
TVIS30014525
Fusion event
HIV-ZFYVE9 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
52707664/52241992 (Hg38)
End
52707637/52241992 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
ZFYVE9
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-222-3p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-130a-3p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-580-5p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-1225-5p ; hsa-mir-1229-5p ; hsa-mir-4295 ; hsa-mir-4328 ; hsa-mir-3666 ; hsa-mir-5002-3p ; hsa-mir-141-5p ; hsa-mir-145-5p ; hsa-mir-5195-3p ; hsa-mir-4643 ; hsa-mir-526b-5p ; hsa-mir-591 ; hsa-mir-6758-5p ; hsa-mir-6856-5p ; hsa-mir-4684-3p ; hsa-mir-503-3p ; hsa-mir-367-5p ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-4755-3p ; hsa-mir-4753-5p ; hsa-mir-6768-3p
Nearest miRNA
hsa-mir-12136/Upstream/405590; hsa-mir-101-1/Downstream/1812087;
Nearest TSS
ENST00000473358/Upstream/25612; ENST00000469134/Downstream/53903;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/99160, chr1-CpG: 72/Downstream/123739
Upstream sequence
CGTAGTAATTACTTAATATTTATAGCTATATTCCCTTTACTGcaacaagcatatattgtgtctaatatataaaaggttctaggctaggtaatggggattc
Downstream sequence
agaggtatataaATTGGAATTTATGATGTCATGGCAATCtttttttttttttttttttttttgagacagagtctctgttgcccaggctggagtgtatggc
Target sequence
aggttctaggctaggtaatggggattc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate