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TVIS30014532
Basic Information
VIS ID
TVIS30014532
Fusion event
HIV-ZYG11B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
53232338/52766666 (Hg38)
End
53232051/52766666 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
ZYG11B
miRNAs that regulate target gene
hsa-mir-21-5p
;
hsa-mir-3149
;
hsa-mir-1303
;
hsa-mir-411-5p
;
hsa-mir-6832-5p
;
hsa-mir-6872-3p
;
hsa-mir-483-5p
;
hsa-mir-4446-5p
;
hsa-mir-5006-3p
;
hsa-mir-4755-5p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-623
;
hsa-mir-3653-3p
;
hsa-mir-377-3p
;
hsa-mir-1248
;
hsa-mir-5088-3p
;
hsa-mir-216b-3p
;
hsa-mir-129-5p
;
hsa-mir-4451
;
hsa-mir-379-5p
;
hsa-mir-3529-5p
;
hsa-mir-4650-3p
;
hsa-mir-4282
;
hsa-mir-4668-5p
;
hsa-mir-3148
;
hsa-mir-651-3p
;
hsa-mir-5582-3p
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548ae-3p
;
hsa-mir-4790-5p
;
hsa-mir-4524a-3p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-3615
;
hsa-mir-4315
;
hsa-mir-8061
;
hsa-mir-4760-5p
;
hsa-mir-376a-5p
;
hsa-mir-6873-3p
;
hsa-mir-3681-3p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-520f-5p
;
hsa-mir-5096
;
hsa-mir-6773-5p
;
hsa-mir-6724-5p
;
hsa-mir-197-3p
;
hsa-mir-6508-3p
;
hsa-mir-4726-5p
;
hsa-mir-4640-5p
;
hsa-mir-6823-5p
;
hsa-mir-4524b-3p
;
hsa-mir-5684
;
hsa-mir-5698
;
hsa-mir-143-5p
;
hsa-mir-6879-3p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-3622b-5p
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-6499-3p
;
hsa-mir-3145-3p
;
hsa-mir-215-3p
;
hsa-mir-6773-3p
;
hsa-mir-5693
;
hsa-mir-500b-3p
;
hsa-mir-3664-5p
;
hsa-mir-514a-5p
;
hsa-mir-4714-5p
;
hsa-mir-200c-5p
;
hsa-mir-550a-3p
;
hsa-mir-550b-3p
;
hsa-mir-8057
;
hsa-mir-924
;
hsa-mir-103b
;
hsa-mir-302c-5p
;
hsa-mir-3143
;
hsa-mir-4662a-5p
;
hsa-mir-4803
;
hsa-mir-552-5p
Nearest miRNA
hsa-mir-12136/Upstream/930264; hsa-mir-101-1/Downstream/1287413;
Nearest TSS
ENST00000473358/Upstream/40157;
ENST00000612017/Downstream/75845;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/39910
,
chr1-CpG: 110/Downstream/75956
Upstream sequence
atgattcagagtaattttttattgaaaccaggacattttaggtgatatgagacttttctgttttagtttgagtcactgacgtcactccagcagtggaagg
Downstream sequence
taggagcactgccttgttactgccagattggggtTAATGTTCTTTGTAAAAATTTTTATAggccaggcacagtggctcacgcctgtaatcccagcacttt
Target sequence
aagtgccaccgcgcctggtctgttactcattttttttcaagcatatttgtttacttttgaaaatttaattgcatttttttatggctcctttaaaatcgttgtcaaataattttaacatttctgttaccttactgttggcatatattgattatctctttttgagtttgaagtcttactggttcttagtatgattcagagtaattttttattgaaaccaggacattttaggtgatatgagacttttctgttttagtt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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