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TVIS30014537
Basic Information
VIS ID
TVIS30014537
Fusion event
HIV-SRSF11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
70696089/70230406 (Hg38)
End
70696286/70230406 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
SRSF11
miRNAs that regulate target gene
hsa-mir-376a-5p
;
hsa-mir-376a-3p
;
hsa-mir-21-5p
;
hsa-mir-423-5p
;
hsa-mir-186-5p
;
hsa-mir-126-5p
;
hsa-mir-576-3p
;
hsa-mir-944
;
hsa-mir-3190-3p
;
hsa-mir-3668
;
hsa-mir-4491
;
hsa-mir-4657
;
hsa-mir-6505-5p
;
hsa-mir-6833-5p
;
hsa-mir-493-3p
;
hsa-mir-3974
;
hsa-mir-4999-3p
;
hsa-mir-5195-5p
;
hsa-mir-6832-3p
;
hsa-mir-4738-3p
;
hsa-mir-376a-2-5p
;
hsa-mir-3935
;
hsa-mir-548t-5p
;
hsa-mir-3609
;
hsa-mir-548ah-5p
;
hsa-mir-548az-5p
;
hsa-mir-510-3p
;
hsa-mir-127-5p
;
hsa-mir-6806-3p
;
hsa-mir-3928-5p
;
hsa-mir-6807-3p
;
hsa-mir-217
;
hsa-mir-509-5p
;
hsa-mir-4418
;
hsa-mir-509-3-5p
;
hsa-mir-100-3p
;
hsa-mir-653-3p
;
hsa-mir-4420
;
hsa-mir-181b-3p
;
hsa-mir-181b-2-3p
;
hsa-mir-556-3p
;
hsa-mir-3682-5p
;
hsa-mir-3171
;
hsa-mir-3662
Nearest miRNA
hsa-mir-101-1/Upstream/2046796; hsa-mir-11399/Downstream/837225;
Nearest TSS
ENST00000473358/Upstream/128;
ENST00000460795/Downstream/1142;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/24647
,
chr1-CpG: 84/Downstream/123644
Upstream sequence
TTAATGTTACCTCCAGTAAATACAATTCCCTCCAGATTTAGCTATTACACTTCGGTGTTAGCTCTTGGTCAGTGTTTTAGAACAGTAGACATAGTCTACG
Downstream sequence
CATGAAAATTAACTGGTGAGGGGCCTCATTGCTATTTTTAAATTGTAGTTTTATTTTTAAATAGTCTTTTTTTAATCAGAGGATCAGATGCATGACTTTT
Target sequence
GTAAGGAATAGTCTTAATTGGTAAAACTAAGATAGCTGAATTTGGAAGGAACTCTTAATAGTAATGGATTTGGGGATTTTTTAGGTTCCTTGGTTAATGTTTGTTTCTTTTGTCTGTTTCTTTTTCTTTCATTTCTACACATTCATGCAGTATTTCATGGTTCTATCAAAGCAGCAGTAAAAAAAATACTCTTGACG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT4
Sample type
PBMC
Age
39
Gender
Male
CpG Island Information
×
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