Basic Information
VIS ID
TVIS30014539
Fusion event
HIV-GBP7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
89634943/89169260 (Hg38)
End
89634682/89169260 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
GBP7
Nearest miRNA
hsa-mir-101-1/Upstream/2811573; hsa-mir-11399/Downstream/4677572;
Nearest TSS
ENST00000473358/Upstream/18804; ENST00000641099/Downstream/6780;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/176339, chr1-CpG: 114/Downstream/354991
Upstream sequence
tacaaacaagtgagtttgtatctctgttttaccatgttatgactaaaatttttaaagtgaaaaaccctgtgacctttgcttgtgtatgtatttatgtttg
Downstream sequence
catgttttgtgtatgtaataattttcccaagatatgtgaaagagctctatttaattggcttaaaGTGTCaacgaagcaaacttaaaagagcctcatgact
Target sequence
ctcctgtggaagctgcagtttaccccaaatttagtccacagcctccatagaattaacagttaaaggcaaatggaaaatctcaaaaggttagccatttgagcaagtaaccttaacttattctgttttttcagaaaaataagtttggatttagctgtcctttttacaaacaagtgagtttgtatctctgttttaccatgttatgactaaaatttttaaagtgaaaaaccctgtgacctttgcttgtgtatgtattta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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