VISDB Viral Integration Site DataBase

VIS ID

TVIS30014540

Fusion event

HIV-TGFBR3 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr1

Cytoband

p22.1

Reference genome

Start

End

92282514/91816752 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-193b-3p ; hsa-mir-181a-5p ; hsa-mir-101-3p ; hsa-mir-6817-3p ; hsa-mir-6873-3p ; hsa-mir-7110-3p ; hsa-mir-541-5p ; hsa-mir-136-3p ; hsa-mir-382-3p ; hsa-mir-218-5p ; hsa-mir-513a-5p ; hsa-mir-369-5p ; hsa-mir-186-5p ; hsa-mir-3681-3p ; hsa-mir-27b-3p ; hsa-mir-216a-3p ; hsa-mir-27a-3p ; hsa-mir-128-3p ; hsa-mir-582-5p ; hsa-mir-202-3p ; hsa-mir-6715a-3p ; hsa-mir-144-3p ; hsa-let-7a-5p ; hsa-let-7c-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-let-7d-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-4638-3p ; hsa-mir-3690 ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-330-3p ; hsa-mir-497-5p ; hsa-mir-195-5p ; hsa-mir-6838-5p ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-424-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-4753-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-130b-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183

Nearest miRNA

hsa-mir-101-1/Upstream/5459065; hsa-mir-11399/Downstream/2030080;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/269653, chr1-CpG: 123/Downstream/68604

Nearest cancer related gene

TGFBR3(TSG, No orient, 0)

Upstream sequence

GTTCCCATATATTGGGCTCAACTGAAACTTTAAACTCATGCAATAACTGTTAATATTCAAGTATAATTTTACCTAGCAGTAAAGTTATATTTTGCACATC

Downstream sequence

CTAATCTCTGAGTACTCATTTATCATCTCTACAACTACACATTTGACAGAACCAAACTGTGGCCCTAAGAAACAAGAATTACTGGCATAGCTAAGAATTC

Target sequence

AAAAGCAAAATGAAGCATTAAGAAATTTAGTTATATACATTCTTTCATATCCCTTTACATAAGCAGAATACAAAGTACTTACTTTTTTTCCCCCAAATGAATACAGGATTTCAACAACATTAAGACATGATTATTTTCACTTACTCCCATATAATAGGTATTCTTATTAAAGAAAACATCTTAATGTCACCATATATGAATTCAT