Basic Information
VIS ID
TVIS30014543
Fusion event
HIV-DR1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p22.1
Reference genome
End
93815559/93350182 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-320a ; hsa-mir-513a-5p ; hsa-mir-513b-5p ; hsa-mir-513c-5p ; hsa-mir-450a-1-3p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548n ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-4259 ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-4425 ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-4495 ; hsa-mir-548am-5p ; hsa-mir-4668-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-137 ; hsa-mir-590-3p ; hsa-mir-3120-3p ; hsa-mir-3185 ; hsa-mir-4635 ; hsa-mir-6507-5p ; hsa-mir-499a-3p ; hsa-mir-499b-3p ; hsa-mir-3616-5p ; hsa-mir-573 ; hsa-mir-7975 ; hsa-mir-5571-3p ; hsa-mir-431-5p ; hsa-mir-4670-3p ; hsa-mir-384 ; hsa-mir-3117-3p ; hsa-mir-3607-3p ; hsa-mir-8083 ; hsa-mir-4759 ; hsa-mir-3169 ; hsa-mir-340-5p ; hsa-mir-4799-5p ; hsa-mir-6739-5p ; hsa-mir-3153 ; hsa-mir-6733-5p ; hsa-mir-4529-5p ; hsa-mir-4715-5p ; hsa-mir-5571-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-4709-3p ; hsa-mir-125b-2-3p ; hsa-mir-4457 ; hsa-mir-629-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-136-5p ; hsa-mir-3121-5p ; hsa-mir-501-5p ; hsa-mir-8080 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-942-5p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-1247-3p ; hsa-mir-1827 ; hsa-mir-25-5p ; hsa-mir-3664-3p ; hsa-mir-3929 ; hsa-mir-4327 ; hsa-mir-4419b ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4478 ; hsa-mir-4649-3p ; hsa-mir-4695-5p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-485-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-5690 ; hsa-mir-6087 ; hsa-mir-665 ; hsa-mir-6884-5p ; hsa-mir-7160-5p ; hsa-mir-3165 ; hsa-mir-363-5p ; hsa-mir-3656 ; hsa-mir-4683 ; hsa-mir-6745 ; hsa-mir-6888-5p ; hsa-mir-20a-3p ; hsa-mir-3680-3p ; hsa-mir-3909 ; hsa-mir-450b-5p ; hsa-mir-4666b ; hsa-mir-4686 ; hsa-mir-4691-5p ; hsa-mir-5011-3p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-6792-3p ; hsa-mir-6852-3p
Nearest miRNA
hsa-mir-101-1/Upstream/6992495; hsa-mir-11399/Downstream/496650;
Upstream sequence
CAAATGCTTTTCAAGTTAGGattttattaatacttttctttaaattaatatatcttttatttCTGTTTTCCTTCTGCCACCCCACAATTACTTATTGAAT
Downstream sequence
ACTACCAATTATTTGGCATCATGCTAGGTACTACTAAGGATATTAAGATAAATGATACTCAATTCCTTCTCTGCCATTAGTCTCTCATTGTTGTCCAAGA
Target sequence
TAAGTAGTAAATAATCGTTTATACAGATATTTTTTCCGAAGGGACACATCTAATTTGCACTGCAAAATTTATCACATAATCAAATGCTTTTCAAGTTAGGattttattaatacttttctttaaattaatatatcttttatttCTGTTTTCCTTCTGCCACCCCACAATTACTTATTGAAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate