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TVIS30014543
Basic Information
VIS ID
TVIS30014543
Fusion event
HIV-DR1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
93815739/93350182 (Hg38)
End
93815559/93350182 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
DR1
miRNAs that regulate target gene
hsa-mir-375
;
hsa-mir-155-5p
;
hsa-mir-320a
;
hsa-mir-513a-5p
;
hsa-mir-513b-5p
;
hsa-mir-513c-5p
;
hsa-mir-450a-1-3p
;
hsa-mir-559
;
hsa-mir-548b-5p
;
hsa-mir-548a-5p
;
hsa-mir-548c-5p
;
hsa-mir-548d-5p
;
hsa-mir-548j-5p
;
hsa-mir-548n
;
hsa-mir-548h-5p
;
hsa-mir-548i
;
hsa-mir-548w
;
hsa-mir-4259
;
hsa-mir-548y
;
hsa-mir-548o-5p
;
hsa-mir-548ab
;
hsa-mir-4425
;
hsa-mir-548ad-5p
;
hsa-mir-548ae-5p
;
hsa-mir-548ak
;
hsa-mir-4495
;
hsa-mir-548am-5p
;
hsa-mir-4668-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548as-5p
;
hsa-mir-548au-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548bb-5p
;
hsa-mir-137
;
hsa-mir-590-3p
;
hsa-mir-3120-3p
;
hsa-mir-3185
;
hsa-mir-4635
;
hsa-mir-6507-5p
;
hsa-mir-499a-3p
;
hsa-mir-499b-3p
;
hsa-mir-3616-5p
;
hsa-mir-573
;
hsa-mir-7975
;
hsa-mir-5571-3p
;
hsa-mir-431-5p
;
hsa-mir-4670-3p
;
hsa-mir-384
;
hsa-mir-3117-3p
;
hsa-mir-3607-3p
;
hsa-mir-8083
;
hsa-mir-4759
;
hsa-mir-3169
;
hsa-mir-340-5p
;
hsa-mir-4799-5p
;
hsa-mir-6739-5p
;
hsa-mir-3153
;
hsa-mir-6733-5p
;
hsa-mir-4529-5p
;
hsa-mir-4715-5p
;
hsa-mir-5571-5p
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-4709-3p
;
hsa-mir-125b-2-3p
;
hsa-mir-4457
;
hsa-mir-629-3p
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-136-5p
;
hsa-mir-3121-5p
;
hsa-mir-501-5p
;
hsa-mir-8080
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-4753-3p
;
hsa-mir-6780a-3p
;
hsa-mir-7111-3p
;
hsa-mir-942-5p
;
hsa-mir-1236-3p
;
hsa-mir-6515-3p
;
hsa-mir-1247-3p
;
hsa-mir-1827
;
hsa-mir-25-5p
;
hsa-mir-3664-3p
;
hsa-mir-3929
;
hsa-mir-4327
;
hsa-mir-4419b
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4478
;
hsa-mir-4649-3p
;
hsa-mir-4695-5p
;
hsa-mir-4722-5p
;
hsa-mir-4768-3p
;
hsa-mir-485-5p
;
hsa-mir-510-5p
;
hsa-mir-512-5p
;
hsa-mir-5690
;
hsa-mir-6087
;
hsa-mir-665
;
hsa-mir-6884-5p
;
hsa-mir-7160-5p
;
hsa-mir-3165
;
hsa-mir-363-5p
;
hsa-mir-3656
;
hsa-mir-4683
;
hsa-mir-6745
;
hsa-mir-6888-5p
;
hsa-mir-20a-3p
;
hsa-mir-3680-3p
;
hsa-mir-3909
;
hsa-mir-450b-5p
;
hsa-mir-4666b
;
hsa-mir-4686
;
hsa-mir-4691-5p
;
hsa-mir-5011-3p
;
hsa-mir-507
;
hsa-mir-557
;
hsa-mir-6792-3p
;
hsa-mir-6852-3p
Nearest miRNA
hsa-mir-101-1/Upstream/6992495; hsa-mir-11399/Downstream/496650;
Nearest TSS
ENST00000473358/Upstream/4247;
ENST00000481583/Downstream/4793;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/3799
,
chr1-CpG: 111/Downstream/97730
Upstream sequence
CAAATGCTTTTCAAGTTAGGattttattaatacttttctttaaattaatatatcttttatttCTGTTTTCCTTCTGCCACCCCACAATTACTTATTGAAT
Downstream sequence
ACTACCAATTATTTGGCATCATGCTAGGTACTACTAAGGATATTAAGATAAATGATACTCAATTCCTTCTCTGCCATTAGTCTCTCATTGTTGTCCAAGA
Target sequence
TAAGTAGTAAATAATCGTTTATACAGATATTTTTTCCGAAGGGACACATCTAATTTGCACTGCAAAATTTATCACATAATCAAATGCTTTTCAAGTTAGGattttattaatacttttctttaaattaatatatcttttatttCTGTTTTCCTTCTGCCACCCCACAATTACTTATTGAAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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