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TVIS30014553
Basic Information
VIS ID
TVIS30014553
Fusion event
HIV-SLC30A7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
101445580/100980024 (Hg38)
End
101445535/100980024 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA1E
Target gene
SLC30A7
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-193b-3p
;
hsa-mir-155-5p
;
hsa-let-7b-5p
;
hsa-mir-221-3p
;
hsa-mir-186-5p
;
hsa-mir-3133
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-2113
;
hsa-mir-4729
;
hsa-mir-5680
;
hsa-mir-548aw
;
hsa-mir-5696
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-1321
;
hsa-mir-4270
;
hsa-mir-4441
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-6754-5p
;
hsa-mir-6799-5p
;
hsa-mir-4728-3p
;
hsa-mir-3714
;
hsa-mir-548an
;
hsa-mir-103a-3p
;
hsa-mir-107
;
hsa-mir-340-5p
;
hsa-mir-1827
;
hsa-mir-4720-3p
;
hsa-mir-185-5p
;
hsa-mir-4306
;
hsa-mir-4644
;
hsa-mir-5192
;
hsa-mir-2681-5p
;
hsa-mir-148a-5p
;
hsa-mir-4763-3p
;
hsa-mir-1207-5p
;
hsa-mir-4804-3p
;
hsa-mir-4484
;
hsa-mir-6768-3p
;
hsa-mir-8077
;
hsa-mir-7160-5p
;
hsa-mir-4663
;
hsa-mir-4680-5p
;
hsa-mir-5590-3p
;
hsa-mir-142-5p
;
hsa-mir-6757-3p
;
hsa-mir-4511
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-1247-3p
;
hsa-mir-2467-3p
;
hsa-mir-3160-3p
;
hsa-mir-377-5p
;
hsa-mir-4257
;
hsa-mir-4487
;
hsa-mir-455-3p
;
hsa-mir-5186
;
hsa-mir-558
;
hsa-mir-6086
;
hsa-mir-6499-3p
;
hsa-mir-6516-5p
;
hsa-mir-6828-5p
Nearest miRNA
hsa-mir-101-1/Upstream/698716; hsa-mir-11399/Downstream/6917199;
Nearest TSS
ENST00000473358/Upstream/18196;
ENST00000414686/Downstream/15126;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/83772
,
chr1-CpG: 31/Downstream/45737
Upstream sequence
TTAGTGAATAATCACCATGACAAAATTGGTATGGCGGAACAGTCATTATACATTATTTAGACTCATTCCTTCTTCCAGTGCCCTTATGATTATTTCCTAC
Downstream sequence
CTTTACCATTGATCTTAAACTGTGCAGGCTAAAAAGAGGAACCAGAACTCCCTTAAGCACTTTTAAGACTATTTAAAAAATAAAGTTTTGTTGGCATTGA
Target sequence
TTTAGACTCATTCCTTCTTCCAGTGCCCTTATGATTATTTCCTAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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