Basic Information
VIS ID
TVIS30014554
Fusion event
HIV-GPSM2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
109443124/108900502 (Hg38)
End
109442971/108900502 (Hg38)
Orient
-
Location type
Intronic
Target gene
GPSM2
miRNAs that regulate target gene
hsa-mir-373-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-5687 ; hsa-mir-32-3p ; hsa-mir-4474-5p ; hsa-mir-4704-3p ; hsa-mir-383-3p ; hsa-mir-3065-3p ; hsa-mir-323a-3p ; hsa-mir-569 ; hsa-mir-378a-5p ; hsa-mir-17-3p ; hsa-mir-4526 ; hsa-mir-3660 ; hsa-mir-103b ; hsa-mir-122-5p ; hsa-mir-143-5p ; hsa-mir-215-3p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-4430 ; hsa-mir-500b-3p ; hsa-mir-504-3p ; hsa-mir-564 ; hsa-mir-5693 ; hsa-mir-5698 ; hsa-mir-6499-3p ; hsa-mir-6773-3p ; hsa-mir-6854-5p ; hsa-mir-6879-3p ; hsa-mir-7705 ; hsa-mir-891a-3p
Nearest miRNA
hsa-mir-101-1/Upstream/1003198; hsa-mir-11399/Downstream/698391;
Nearest TSS
ENST00000473358/Upstream/2966; ENST00000643921/Downstream/1402;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/23086, chr1-CpG: 68/Downstream/62557
Upstream sequence
taatttttgtatttttagtagagacggggtttcgccatgttggccaggctagtctgggactcctgacctcaagtgatccgcccacctcagcctcccaaag
Downstream sequence
tgctgggattacaggcgtgaaccaccacacccagccTGGAATTGTTATCAGGGCCAAACAAGAAGGCTAACAATGTAGATCCATATCCTTCCGGATACAA
Target sequence
ctgcctcagcttctgagcagctgggattacaggtgtctgccaccacgcccagctaatttttgtatttttagtagagacggggtttcgccatgttggccaggctagtctgggactcctgacctcaagtgatccgcccacctcagcctcccaaag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate