Basic Information
VIS ID
TVIS30014555
Fusion event
HIV-CD53 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
111421307/110878685 (Hg38)
End
111421055/110878685 (Hg38)
Orient
-
Location type
Intronic
Target gene
CD53
Nearest miRNA
hsa-mir-101-1/Upstream/1279718; hsa-mir-11399/Downstream/1583085;
Nearest TSS
ENST00000473358/Upstream/5502; ENST00000464329/Downstream/1552;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/97874, chr1-CpG: 87/Downstream/84574
Upstream sequence
TTACATTTGCTTTCTATTGCTGGATTTTTCAACTTTTTCTAATAGGTTTGAATGGAGTAAGAAATGTGTTCTAATAATATATATTCTCAATCTTAGCTTA
Downstream sequence
CAAAGGTGTTTCTCTACCAAACACTTCCATTCACTGAAAGAAAACAATTTATGCATCTTAAAGAAACTGTGCTTACATTTGCCTTTTATTGCTGGGATTT
Target sequence
gaaatgtatatggagaagtgtctggaaagacgtttgccaaaatgctaatgatggttatctctgggaggtgggatttcagaagattttatgctttcttctttatacttttctttattttttaaatGTAGAATTTTTTTTTAAAGAAAGCATGCTTACATTTGCTTTCTATTGCTGGATTTTTCAACTTTTTCTAATAGGTTTGAATGGAGTAAGAAATGTGTTCTAATAATATATATTCTCAATCTTAGCTTA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate