Basic Information
VIS ID
TVIS30014559
Fusion event
HIV-CEPT1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
111714564/111171942 (Hg38)
End
111714687/111171942 (Hg38)
Orient
+
Location type
Intronic
Target gene
CEPT1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-23b-3p ; hsa-mir-183-5p ; hsa-mir-26a-5p ; hsa-mir-670-3p ; hsa-mir-580-3p ; hsa-mir-6770-5p ; hsa-mir-4797-3p ; hsa-mir-1253 ; hsa-mir-545-5p ; hsa-mir-100-3p ; hsa-mir-186-5p ; hsa-mir-3133
Nearest miRNA
hsa-mir-101-1/Upstream/1572975; hsa-mir-11399/Downstream/1289828;
Nearest TSS
ENST00000473358/Upstream/24265; ENST00000483427/Downstream/1196;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/31261, chr1-CpG: 91/Downstream/31749
Upstream sequence
attctcccgcctcagcctcctgagtagttggaattacaggcatgcgccaccacacctgttaattttgtattgttagtagagacggggtttctccatgttg
Downstream sequence
AAGATGTTCATGTACCTTCATAGATATAGAAAATTGTGGTTAGTATCATTTAATTTTCTCCCTCTACAACTTTAGGCTGTAGAAATCTAATGCGACACAT
Target sequence
gtcaggctggtctcaaactccctacctcaggtgatccgcctgcctcggcctccccaaagtgctgggattacaggcgtgagccaccacgcccagccAGGAGATTATTTTAAAGCAGCACCAGTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate