Basic Information
VIS ID
TVIS30014566
Fusion event
HIV-ST7L integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
113126021/112583399 (Hg38)
End
113126105/112583399 (Hg38)
Orient
+
Location type
Intronic
Target gene
ST7L
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-mir-18a-3p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-7154-3p ; hsa-mir-7106-5p ; hsa-mir-4731-5p ; hsa-mir-7515 ; hsa-mir-7113-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4756-5p ; hsa-mir-4270 ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-23a-3p
Nearest miRNA
hsa-mir-101-1/Upstream/121566; hsa-mir-11399/Downstream/298651;
Nearest TSS
ENST00000473358/Upstream/27523; ENST00000485542/Downstream/27507;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/73720, chr1-CpG: 76/Downstream/35570
Upstream sequence
AAACCCTCTGGCCATAAAAATAGCAGGAAGCAGCATCATTGCTGATTCTAACATCTTTGGTAAAAAAAAATCTCAATCATAACTGGTAGAGCATATCTAA
Downstream sequence
AAGTATGAGGTTGGATTTTGGGCTAAGAATCAGATGGTGTGAAAGGGGCCACTCCCTAGCACTATATGCAGATACACAGTCTGAAGAACCAACCAAATAA
Target sequence
GAACAGAAAGGACTTCTGTTGCTATGGCTCATCTGATCTCAAGCACATCATGGAGAAAAATCAACCAAAGAAAGAATCAATGCC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate