Basic Information
VIS ID
TVIS30014568
Fusion event
HIV-ATP1A1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
116938166/116395544 (Hg38)
End
116938051/116395544 (Hg38)
Orient
-
Location type
Intronic
Target gene
ATP1A1
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-340-5p ; hsa-mir-26b-5p ; hsa-mir-93-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-23b-3p ; hsa-mir-30d-5p ; hsa-mir-197-3p ; hsa-mir-196a-5p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-18a-5p ; hsa-let-7b-5p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-155-3p ; hsa-mir-3160-5p ; hsa-mir-4746-3p ; hsa-mir-3124-3p ; hsa-mir-1250-5p ; hsa-mir-6753-5p ; hsa-mir-1911-3p
Nearest miRNA
hsa-mir-101-1/Upstream/3513415; hsa-mir-1182/Downstream/164480;
Nearest TSS
ENST00000473358/Upstream/6817; ENST00000479960/Downstream/3927;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/21353, chr1-CpG: 44/Downstream/23016
Upstream sequence
TAGTATTAAAATATGATGGTGTAAACACACGAGGAATTAAAAATTTTTTGGAAAGCAATTGTGTAAAAAAGAAATGTAAGCAAAGTAAAAACAGCAAAAG
Downstream sequence
ACTTGAAGTTTTAAAATACTTGCATTATTCTAAGTTAATGTACCTTATGCAATGAATGGCATATCTTCTGTGTTTTCAGTTAACTGTTTGTTAATGAGTG
Target sequence
CCAGAAAAGACCAGATAGTATTAAAATATGATGGTGTAAACACACGAGGAATTAAAAATTTTTTGGAAAGCAATTGTGTAAAAAAGAAATGTAAGCAAAGTAAAAACAGCAAAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate