Basic Information
VIS ID
TVIS30014569
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
117293636/116751014 (Hg38)
End
117293702/116751014 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/79197; hsa-mir-1182/Downstream/343629;
Nearest TSS
ENST00000473358/Upstream/56902; ENST00000369477/Downstream/3371;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/83015, chr1-CpG: 126/Downstream/158567
Nearby gene
CD2(No orient, 3449)
Upstream sequence
aaggctgcagtatgctgtggtgctgtggtcataccactgcactccatcttgagcaacagagcaagaccctgtctctaaaattaaaaaaaaaTTGTTATGC
Downstream sequence
TTTACATAGAAAGTTTTCACATTTTACAGAGTCAAATCTACTGACCTCTTTCTTTTTCATTGTTTCTGCCCTTGAAGCCATGCTCATCACTCAGAATTGA
Target sequence
CTTTGTCATGTATCTTGCAAGTAATTTGCTCCTTTTAGTACGTTGTCTTTAATTTTTTTATGGCTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate