Basic Information
VIS ID
TVIS30014581
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
150190708/150218408 (Hg38)
End
150190624/150218408 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1F
Nearest miRNA
hsa-mir-101-1/Upstream/1830045; hsa-mir-1182/Downstream/273937;
Nearest TSS
ENST00000473358/Upstream/59003; ENST00000582010/Downstream/8322;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/67520, chr1-CpG: 97/Downstream/16215
Nearby gene
ANP32E(No orient, 8)
Upstream sequence
ATCACATCCAAGTATTTAAATCAGTTAACTTTCAAGCTGTTAGTTTTTAAAAAGACCTTCAAAGCCGCTAATGGTATTGTTGAAAAAGTGAATGCTATAC
Downstream sequence
ACTGAAACTAATCATTATAACAAATCTTCAATTTATTTGAAGCAATTCAGTTTCAAAAACTTTAAGTTACAGCAGTCACAGAAAAAAACAGGGAACAGTC
Target sequence
TAAATCAGTTAACTTTCAAGCTGTTAGTTTTTAAAAAGACCTTCAAAGCCGCTAATGGTATTGTTGAAAAAGTGAATGCTATAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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