Basic Information
VIS ID
TVIS30014595
Fusion event
HIV-GON4L integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q22
Reference genome
GRCh37/hg19
Start
155812766/155842975 (Hg38)
End
155812628/155842975 (Hg38)
Orient
-
Location type
Intronic
Target gene
GON4L
miRNAs that regulate target gene
hsa-mir-106b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/496530; hsa-mir-1182/Downstream/108298;
Nearest TSS
ENST00000473358/Upstream/21455; ENST00000368324/Downstream/10430;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/96858, chr1-CpG: 27/Downstream/16343
Upstream sequence
aattataatataaccaatatggaagggcacccactccccattaggtattgttaagcactcccactgctgttaaacttcggggaatcactagctaggtaca
Downstream sequence
cctgtcccggattaaacaaacctgtttttggtgaatccctacaggcacaagaggaggacaccatgacctacacctgcaaacctctggaagacttaaagtt
Target sequence
aaaaaaaaaaacttggaaagaaggattccttgaagatcaattataatataaccaatatggaagggcacccactccccattaggtattgttaagcactcccactgctgttaaacttcggggaatcactagctaggtaca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate