Basic Information
VIS ID
TVIS30014599
Fusion event
HIV-B4GALT3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
161153754/161183964 (Hg38)
End
161153650/161183964 (Hg38)
Orient
-
Location type
Intronic
Target gene
B4GALT3
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-98-5p ; hsa-mir-96-5p ; hsa-mir-125b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1283885; hsa-mir-1182/Downstream/43222;
Nearest TSS
ENST00000473358/Upstream/5996; ENST00000475570/Downstream/11787;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/6303, chr1-CpG: 41/Downstream/18055
Nearby gene
ADAMTS4(No orient, 5783)
Upstream sequence
tttcatcatgtcccccaggctggtcttgaacttctggcctcaagtgatcctcccaccttggcctcccaaagtgctgggactacaggtatgggtcactgtg
Downstream sequence
cccagccTTACTGCTCACTTCTAGAAGGAGAGACAGGcacctcctccagaaacacttctgtggcctcatattctgtgctaggtgcccctccttgatcatg
Target sequence
caggtttcatcatgtcccccaggctggtcttgaacttctggcctcaagtgatcctcccaccttggcctcccaaagtgctgggactacaggtatgggtcactgtg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate