Basic Information
VIS ID
TVIS30014606
Fusion event
HIV-KIFAP3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
170043990/170074849 (Hg38)
End
170044082/170074849 (Hg38)
Orient
+
Location type
Intronic
Target gene
KIFAP3
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-671-3p ; hsa-mir-425-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1699228; hsa-mir-1182/Downstream/76529;
Nearest TSS
ENST00000473358/Upstream/111; ENST00000367764/Downstream/10359;
Nearest CpG islands
chr1-CpG: 30/Target, None/Upstream, None/Downstream
Nearby gene
KIFAP3(No orient, 5934)
Upstream sequence
TCAGTCTGAGGCGGTGGCCTCAGAGTTTGACGCACCGGGGAGCCGAGCAGGGAAGTTTTGGTGCAGTTTTGAGCGTCCGTGTATAAGGAGTGGCTCCGTA
Downstream sequence
CTATACAGCAGTCCAGCTAATAAGGGAGGTTTCTATTTGGGGGCCTGAATGGCCCTGATTGCACTTACAAGCTCTAACTTATGGAGATAATCTGACCGTT
Target sequence
GTCACCGCCCCCTTGAGGATGGGAATAGAAAGGGCTGTCAGGTCAGCTTGAAAGGAGAGAGGGGAATCCGATAACCTTTTAGTTAGCGAATG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate