Basic Information
VIS ID
TVIS30014607
Fusion event
HIV-DNM3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
172318820/172349680 (Hg38)
End
172318995/172349680 (Hg38)
Orient
+
Location type
Intronic
Target gene
DNM3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/205036; hsa-mir-1182/Downstream/3618690;
Nearest TSS
ENST00000473358/Upstream/204886; ENST00000491124/Downstream/29338;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/507495, chr1-CpG: 35/Downstream/94047
Upstream sequence
AATTATAAAATATCCTGTTCTGAATTTCATTTCAAGATAATGTGAATATAGCAATACATGATCAAATATCTATTTTCTAAATTGAGATTTTAAAAATTCC
Downstream sequence
CATATTATTTATACAATGATATGTGAAGAGGATTACTATAATGCAAGAGGTTAAAAACATAGAAGCACCAAGCCCTCATGTATATAGAAAACTCATGCTA
Target sequence
CAAACTTCATCCCCTGAGTTGAATTCACTAGAATGAAATAAATGAAGACAATGTTCACTAAGCTTCTAAAGAATCCACATGTTAATTGGATCAGTTTGCCCAAAGACTATTTTTGCCTTTAGGATTTATTATTCTGAATTAAGTCATTATATGGTTGAGTGATTATGTAAAAAAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate