Basic Information
VIS ID
TVIS30014608
Fusion event
HIV-RC3H1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
173917636/173948498 (Hg38)
End
173917603/173948498 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1G
Target gene
RC3H1
miRNAs that regulate target gene
hsa-mir-877-5p ; hsa-mir-423-5p ; hsa-mir-218-5p ; hsa-mir-190a-3p ; hsa-mir-5689 ; hsa-mir-5580-3p ; hsa-mir-1277-5p ; hsa-mir-4422 ; hsa-mir-548e-5p ; hsa-mir-3924 ; hsa-mir-410-3p ; hsa-mir-369-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-5011-5p ; hsa-mir-5692b ; hsa-mir-5692c ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-513a-3p ; hsa-mir-1305 ; hsa-mir-627-3p ; hsa-mir-550b-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-1247-3p ; hsa-mir-3192-5p ; hsa-mir-3689d ; hsa-mir-377-5p ; hsa-mir-6086 ; hsa-mir-6134 ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7847-3p
Nearest miRNA
hsa-mir-101-1/Upstream/1803854; hsa-mir-1182/Downstream/2019872;
Nearest TSS
ENST00000473358/Upstream/7049; ENST00000424181/Downstream/13317;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/79719, chr1-CpG: 93/Downstream/73169
Upstream sequence
caatcttgaaGAAatatatatatatatataatgacctagtatatatatatgcatacaaatatatatttatccctatataatgttacacatatatatagac
Downstream sequence
acacaaatatataGTTTGTATGCACATTAACATTTGAGAAATACTAGGTTAGACTTCTTTCACCTATTTGGGAGGTTTTCAATTACCTCTAGATTGGATT
Target sequence
tatccctatataatgttacacatatatatagac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate