Basic Information
VIS ID
TVIS30014610
Fusion event
HIV-NIBAN1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
184930122/184960990 (Hg38)
End
184930165/184960990 (Hg38)
Orient
+
Location type
Intronic
Target gene
NIBAN1
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-124-3p ; hsa-mir-93-5p ; hsa-mir-484 ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-3678-3p ; hsa-mir-2467-3p ; hsa-mir-4699-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-888-5p ; hsa-mir-7849-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-526b-3p ; hsa-mir-106a-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-4474-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-8063 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-1273a ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-212-5p ; hsa-mir-6849-3p ; hsa-mir-1228-3p ; hsa-mir-508-5p
Nearest miRNA
hsa-mir-101-1/Upstream/4522600; hsa-mir-1182/Downstream/7755338;
Nearest TSS
ENST00000473358/Upstream/70805; ENST00000566476/Downstream/13560;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/205686, chr1-CpG: 95/Downstream/12740
Upstream sequence
aagtgctgggattacaggcgtaagccaccacgctcagccAGGCAACAAAATATTAATAGGCATCCCCTCCCATCAAACCTCCCTCTTGCTCACTACACTC
Downstream sequence
TCCTCCCCCTTCTATATGCCGTTCtttttttttttttttttttttttttttttcagacggagtcttgctctgtcgcccaggctggagtgcagtggcgcga
Target sequence
CCAACATAACACCCTTTCTTCAATTCCTTCAAGTACTTCCCCC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate