Basic Information
VIS ID
TVIS30014634
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
198735574/198766445 (Hg38)
End
198735686/198766445 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/2183964; hsa-mir-1182/Downstream/92428;
Nearest TSS
ENST00000473358/Upstream/14090; ENST00000422480/Downstream/60771;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/607211, chr1-CpG: 36/Downstream/1268901
Nearby gene
PTPRC(-8969) ;
Nearest cancer related gene
PTPRC(TSG, -8969) ;
Upstream sequence
aaaaatgctaattaaaacttcattgagataacaattttcaatagtaaatatatcctgttgtcagggttgtggggaaataagaactttcattattttacca
Downstream sequence
ctatttagttacaaaatatgtgtacagattatttattacatcttcctttgaagtgggaaattattggaaacaactaaagtgcccatctatagctattcag
Target sequence
gtacaaaataaacaaccttaaaaaggacaatgtggcaatagctatcaaatttataggtgtttctacatttacctagaaactctacatctggggagttaccctcgaggaatat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate