Basic Information
VIS ID
TVIS30014635
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
200202279/200233151 (Hg38)
End
200202344/200233151 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/1373998; hsa-mir-1182/Downstream/1486357;
Nearest TSS
ENST00000473358/Upstream/189341; ENST00000635220/Downstream/82816;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/85075, chr1-CpG: 24/Downstream/68997
Upstream sequence
CACCTGTTTAGAAAAATACCACTGAGATGGTCAAGAGGGGCCTTGTTCTCAATATTCTCCATCAACTCTGCCACACTTGTACAAGTTTCATTTACATTTT
Downstream sequence
CCTGTATCATCTTATTAAGCTTTTATGAAAAATCAATGGAGTTCCATCATCTCACGAGGCTCTTCCTCACACAGTTGTCAGTGTGAGTGGAGAAGTCTAT
Target sequence
CTTATCCAATTACATCTTGCTCAATTCCTCACTACAATTTATAGCAAACTTTACAAAGCTTTTGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate