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TVIS30014638
Basic Information
VIS ID
TVIS30014638
Fusion event
HIV-ZC3H11A integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
203771882/203802754 (Hg38)
End
203771696/203802754 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZC3H11A
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-1-3p
;
hsa-mir-16-5p
;
hsa-let-7b-5p
;
hsa-mir-27b-3p
;
hsa-mir-129-5p
;
hsa-mir-503-3p
;
hsa-mir-1238-5p
;
hsa-mir-4460
;
hsa-mir-4481
;
hsa-mir-4536-5p
;
hsa-mir-4727-3p
;
hsa-mir-4745-5p
;
hsa-mir-4758-5p
;
hsa-mir-6504-3p
;
hsa-mir-185-5p
;
hsa-mir-4306
;
hsa-mir-4644
;
hsa-mir-5192
;
hsa-mir-6805-3p
;
hsa-mir-5691
;
hsa-mir-582-5p
;
hsa-mir-101-3p
;
hsa-mir-144-3p
;
hsa-mir-137
;
hsa-mir-3591-5p
;
hsa-mir-6857-3p
;
hsa-mir-4494
;
hsa-mir-140-5p
;
hsa-mir-6718-5p
;
hsa-mir-203b-5p
;
hsa-mir-4499
;
hsa-mir-5010-3p
;
hsa-mir-2113
;
hsa-mir-4752
;
hsa-mir-6833-5p
;
hsa-mir-4753-3p
;
hsa-mir-7847-3p
;
hsa-mir-6770-5p
;
hsa-mir-130b-5p
;
hsa-mir-425-5p
;
hsa-mir-3154
Nearest miRNA
hsa-mir-101-1/Upstream/1799518; hsa-mir-1182/Downstream/1645548;
Nearest TSS
ENST00000473358/Upstream/3419;
ENST00000480354/Downstream/12151;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/6589
,
chr1-CpG: 28/Downstream/58625
Upstream sequence
TGGAAGATGGAGTTTTTTTTCATGATCCTTTAACTCTCAAGTTCATCTTTAAATGAACTCtttttttttgttttttttttgttttgttttgttttgtttt
Downstream sequence
tgAGGAGATAACTAACCCTAGCTGTCTCCAGTCTGACAAAGGTTATTTGAATGGACTTAATCTCCCAGTAGTTGGGAGATGTTTTAAAAACACATGCTGT
Target sequence
GTGAAGAAATCTTGAAGACCAGAAATTGGATCTTACTGAAAAACTGATGtttttttgttttttttttaaattatattGTTCAGCTATGGAAGATGGAGTTTTTTTTCATGATCCTTTAACTCTCAAGTTCATCTTTAAATGAACTCtttttttttgttttttttttgttttgttttgttttgtttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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