Basic Information
VIS ID
TVIS30014639
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
204763726/204794598 (Hg38)
End
204763892/204794598 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/2791362; hsa-mir-1182/Downstream/653704;
Nearest TSS
ENST00000473358/Upstream/108865; ENST00000493914/Downstream/34053;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/108841, chr1-CpG: 15/Downstream/187256
Nearby gene
NFASC(No orient, 34055)
Upstream sequence
ACCACAGGGAGTCTCCTAATCCCAGCCACACATTCCCCAGAGCAGGTGCCACAAGCCCAGAGACAAGTCACCATGGGAAGGTGGATGTCAGGGCAGCTGA
Downstream sequence
ttcctgctgttattttctgtttgtctcatttcctctcacttgttttaatgtactttacgctgccttaaatccattttggaacaaggtggggaatagataa
Target sequence
GCCCTGAGGGTCTTGGTAATGAAAAACTCCCCACCAACACtatcactggtcctgcttccctttttgaattggatgctaaggagcctagagctaaatttacagcccatctttagcaagcacataatacttcacttcatacatttggtgtggaaacctccatctacaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate