Basic Information
VIS ID
TVIS30014640
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
204763731/204794603 (Hg38)
End
204763485/204794603 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/2791367; hsa-mir-1182/Downstream/653699;
Nearest TSS
ENST00000473358/Upstream/108870; ENST00000493914/Downstream/34048;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/108846, chr1-CpG: 15/Downstream/187251
Nearby gene
NFASC(No orient, 34050)
Upstream sequence
AGGGAGTCTCCTAATCCCAGCCACACATTCCCCAGAGCAGGTGCCACAAGCCCAGAGACAAGTCACCATGGGAAGGTGGATGTCAGGGCAGCTGAGCCCT
Downstream sequence
GAGGGTCTTGGTAATGAAAAACTCCCCACCAACACtatcactggtcctgcttccctttttgaattggatgctaaggagcctagagctaaatttacagccc
Target sequence
TCCCATTCCACTGCTGGAAGCCACCAGGAAGACAGTACTATCTACACAACTCTCTGTCTCCTAAAGGAATTCTGGGCATAGTCTGGGTGTTTCAGCCAGGCCCCTCCCAAGAGAAGTTCAAGGTTGAACCCAACCTGCTGGACCACAGGGAGTCTCCTAATCCCAGCCACACATTCCCCAGAGCAGGTGCCACAAGCCCAGAGACAAGTCACCATGGGAAGGTGGATGTCAGGGCAGCTGAGCCCT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate