Basic Information
VIS ID
TVIS30014642
Fusion event
HIV-LPGAT1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
211981735/211808393 (Hg38)
End
211981669/211808393 (Hg38)
Orient
-
Location type
Intronic
Target gene
LPGAT1
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-155-5p ; hsa-mir-181a-5p ; hsa-mir-21-5p ; hsa-mir-19b-3p ; hsa-let-7b-5p ; hsa-mir-193b-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-5089-5p ; hsa-mir-4794 ; hsa-mir-664a-5p ; hsa-mir-6871-5p ; hsa-mir-8076 ; hsa-mir-892b ; hsa-mir-6885-3p ; hsa-mir-3689f ; hsa-mir-3689e ; hsa-mir-3689b-5p ; hsa-mir-3689a-5p ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-4501 ; hsa-mir-5586-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-101-1/Upstream/2184883; hsa-mir-1182/Downstream/269220;
Nearest TSS
ENST00000473358/Upstream/15067; ENST00000429499/Downstream/21453;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/132559, chr1-CpG: 128/Downstream/21696
Upstream sequence
gagctgagatcacgccattgcactccagtctgcgcaacaagggcgaaactccgtctcaaaaaaaaaaaaaaaacctctcaaaactcagcattaagagaac
Downstream sequence
aaactacccaattaaaaaaattaagaaaagacttggacacttcaccaaagagaacacagatggcaaataactatatgaaaagatgttcaacatcattagc
Target sequence
caacaagggcgaaactccgtctcaaaaaaaaaaaaaaaacctctcaaaactcagcattaagagaac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate