Basic Information
VIS ID
TVIS30014650
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
GRCh37/hg19
Start
226090619/225902919 (Hg38)
End
226090679/225902919 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/1504608; hsa-mir-1182/Downstream/19161;
Nearest TSS
ENST00000473358/Upstream/13773; ENST00000366814/Downstream/8463;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/14939, chr1-CpG: 88/Downstream/21023
Nearby gene
LEFTY1(No orient, 13773)
Nearest cancer related gene
LEFTY1(TSG, No orient, 13773)
Upstream sequence
taagtgaaagaagtcaatctggaaaggccatatatatatgattgcaactatatgatattctggaaaagacaaagctatggagacagtaaaaaaatgtgtg
Downstream sequence
cagtgaaactactctgtgtgttactgtactggtagacacatgcgtttatacatttgttcaaaccatcaaatgtgcgccaagagccaaccctaatgtaaac
Target sequence
gtttccaggggctagagaggaggaagggatgaaccggcagagcacagagaatttttaggg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate