Basic Information
VIS ID
TVIS30014655
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.13
Reference genome
GRCh37/hg19
Start
229890852/229755105 (Hg38)
End
229890761/229755105 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/1292953; hsa-mir-1182/Downstream/1264723;
Nearest TSS
ENST00000473358/Upstream/104258; ENST00000445339/Downstream/130647;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/128553, chr1-CpG: 171/Downstream/311642
Nearby gene
URB2(No orient, 94906)
Upstream sequence
GCACAATGACAAGGCTTTGATTGTCAACCACTGTAGCTGGCTCCAGCTTTGCTTGGCTTTGACAGATGAAAAGCCATTTTCCACATTGTAGGCCTGCTTC
Downstream sequence
CTGTGGTTTCATCCAGTCCAGTGAGTATTCGGCCCTGTGATTGACACAACCTCAGAATGTGTATGCACCCCCAGAAGACTGTCGTCTGAAAGGAGGGGAA
Target sequence
CAAGGCTTTGATTGTCAACCACTGTAGCTGGCTCCAGCTTTGCTTGGCTTTGACAGATGAAAAGCCATTTTCCACATTGTAGGCCTGCTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate