Basic Information
VIS ID
TVIS30014658
Fusion event
HIV-TARBP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
GRCh37/hg19
Start
234529299/234393553 (Hg38)
End
234529256/234393553 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
TARBP1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-29c-3p
Nearest miRNA
hsa-mir-101-1/Upstream/87014; hsa-mir-1537/Downstream/796481;
Nearest TSS
ENST00000473358/Upstream/829; ENST00000429507/Downstream/7349;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/19798, chr1-CpG: 159/Downstream/84637
Upstream sequence
AAGCCCCAAATACCTCACAGGTCCTGCACAGTCCTGCACAGAACACCTGGGATCATTAAGATTGTTCCCAGCACAATGCTAAGCTCATCATGTCGCATAC
Downstream sequence
ATTCCTTTGAAGCTCCCGTGGCAGTGGATTAATTAAAAAATGTTGAAGACCAAAAGCTTTCAGGCAAAGCTCCCAGAAAACTCCAACTTTACCTCCTAAA
Target sequence
AAGATTGTTCCCAGCACAATGCTAAGCTCATCATGTCGCATAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate