Basic Information
VIS ID
TVIS30014663
Fusion event
HIV-CHM integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
241797242/241633940 (Hg38)
End
241797164/241633940 (Hg38)
Orient
-
Location type
Exonic
Target gene
CHM
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/501594; hsa-mir-3124/Downstream/1712236;
Nearest TSS
ENST00000473358/Upstream/32762; ENST00000496914/Downstream/5309;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/114128, chr1-CpG: 20/Downstream/5941
Upstream sequence
CTCAGAGGATTCTAGTTTGGCCATTACTACATTATTGGTTCCAGGAGCCTCTGGCTGCTTATCATCACCATCAAAGATAATGTCTTCTGGATTTGGAGGT
Downstream sequence
GGAGGGCAGAATTCTTCAGTTGGAAAGATCTCCTGGAAAAGTGTTTCAGCTTGCTTGACAGCATGCTCATTTCCCAGGCCACAGTCAGGCCCAGAGCAGA
Target sequence
ATTACTACATTATTGGTTCCAGGAGCCTCTGGCTGCTTATCATCACCATCAAAGATAATGTCTTCTGGATTTGGAGGT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate