Basic Information
VIS ID
TVIS30014664
Fusion event
HIV-AKR1C8P integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
5212447/5170484 (Hg38)
End
5212592/5170484 (Hg38)
Orient
+
Location type
Intronic
Target gene
AKR1C8P
miRNAs that regulate target gene
hsa-mir-9-5p
Nearest miRNA
hsa-mir-5699/Upstream/1179225; hsa-mir-107/Downstream/981712;
Nearest TSS
ENST00000439456/Upstream/65209; ENST00000469875/Downstream/24978;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/343879, chr10-CpG: 54/Downstream/241984
Upstream sequence
ttggtctgctttattatacttggcttaattatttgtatacagtgcagcaagaataattatttattacataggccttttaaattagctttgatggaacttt
Downstream sequence
cattctttacttaccatggatcagaaaccctgtacagggactctgtagacaaaatatgaggttagttttccaagggctttattggcttcataagttaagt
Target sequence
gttccatagaaggaatctgagataaggcctttttaaagccaaccccatttatgaatttgtaccattaaatacctatgagttggtgaatttctcttctctttgaggtcccaagataacttagggttcctggcctgctagaaagtga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate