Basic Information
VIS ID
TVIS30014665
Fusion event
HIV-chr10 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
6390931/6348969 (Hg38)
End
6390662/6348969 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3155a/Upstream/196692; hsa-mir-107/Downstream/5781791;
Nearest TSS
ENST00000439456/Upstream/71282; ENST00000391437/Downstream/1347;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/128061, chr10-CpG: 77/Downstream/230976
Nearby gene
LINC02656(+1347) ;
Upstream sequence
AATTTAATAGAGCTAGAACCATAAGATGAATGTATTTATCTTCAATCAAAGATGACATGTTGGACAGATTCCTTCATTCATCACTTTTCTGTTATGTTTA
Downstream sequence
GCCCTAAGGGAAGTCTTTTTTAGATACGTAAGATGCACCTTCAGGGTTAAAGCATCTAGTCCAGTCTGAATAAAACATCAAAAGCACCTACAATCCCAAG
Target sequence
GCTTCTCTTCTTTGAGATCCATACTTGATTTGAAAAATCACCACTTGAGCGGCACCTGGTGATTACGTAACCATTCAACTCTGTGTTTTATCCTAGGGCTAGGTAAGAAATTGAAAATCCAGCCTGAAATAATTAGTTTAGCTGCAGACAGGGTGTATTAAACAGACTCAATTTAATAGAGCTAGAACCATAAGATGAATGTATTTATCTTCAATCAAAGATGACATGTTGGACAGATTCCTTCATTCATCACTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate