Basic Information
VIS ID
TVIS30014666
Fusion event
HIV-LOC105376387 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p14
Reference genome
GRCh37/hg19
Start
6991619/6949657 (Hg38)
End
6991481/6949657 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105376387
Nearest miRNA
hsa-mir-3155a/Upstream/797380; hsa-mir-107/Downstream/5181103;
Nearest TSS
ENST00000439456/Upstream/29185; ENST00000420049/Downstream/147495;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/368977, chr10-CpG: 30/Downstream/222223
Upstream sequence
atttatcccatcttgggagccccatcctcatgacctcatttaaacttaatcacctcccaaaggccctatctctaaatacatcacattgcacgttagggag
Downstream sequence
tccacataagaattttgggggaactcaaacattcagtccataATATTGGCTAAATTTGCGATGTAGGTTACAGGGGCAGTAAAAGTCTGCAAATCTTGAA
Target sequence
cttcttttcctcttccttgttctttattttctaaggacatttatcccatcttgggagccccatcctcatgacctcatttaaacttaatcacctcccaaaggccctatctctaaatacatcacattgcacgttagggag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate