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TVIS30014667
Basic Information
VIS ID
TVIS30014667
Fusion event
HIV-DHTKD1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p14
Reference genome
GRCh37/hg19
Start
12164240/12122241 (Hg38)
End
12164176/12122241 (Hg38)
Orient
-
Location type
Exonic
Target gene
DHTKD1
miRNAs that regulate target gene
hsa-mir-1296-5p
;
hsa-mir-92a-3p
;
hsa-mir-16-5p
;
hsa-let-7b-5p
;
hsa-mir-129-5p
;
hsa-mir-1228-5p
;
hsa-mir-6881-5p
;
hsa-mir-6787-5p
;
hsa-mir-663a
;
hsa-mir-1908-5p
;
hsa-mir-7150
;
hsa-mir-4736
;
hsa-mir-4763-3p
;
hsa-mir-1207-5p
;
hsa-mir-4695-3p
;
hsa-mir-4772-3p
;
hsa-mir-6787-3p
;
hsa-mir-1304-3p
;
hsa-mir-6736-3p
;
hsa-mir-6890-3p
;
hsa-mir-4482-3p
;
hsa-mir-7159-3p
;
hsa-mir-1238-3p
;
hsa-mir-670-3p
;
hsa-mir-4753-3p
;
hsa-mir-6873-3p
;
hsa-mir-6881-3p
;
hsa-mir-6780a-3p
;
hsa-mir-7111-3p
;
hsa-mir-130b-5p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-138-2-3p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-6878-3p
;
hsa-mir-640
;
hsa-mir-378a-5p
;
hsa-mir-6778-3p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-3653-5p
;
hsa-mir-150-5p
;
hsa-mir-212-5p
;
hsa-mir-186-3p
;
hsa-mir-6849-3p
;
hsa-mir-764
;
hsa-mir-125a-3p
;
hsa-mir-1226-3p
;
hsa-mir-5585-3p
;
hsa-mir-6783-3p
;
hsa-mir-4279
;
hsa-mir-1343-3p
;
hsa-mir-23b-5p
;
hsa-mir-23a-5p
;
hsa-mir-1976
;
hsa-mir-6742-3p
;
hsa-mir-6852-5p
;
hsa-mir-939-3p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-660-3p
;
hsa-mir-3934-5p
;
hsa-mir-5586-5p
;
hsa-mir-6512-3p
;
hsa-mir-6720-5p
;
hsa-mir-6746-3p
Nearest miRNA
hsa-mir-3155a/Upstream/5969964; hsa-mir-107/Downstream/8519;
Nearest TSS
ENST00000439456/Upstream/3462;
ENST00000457034/Downstream/7396;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/52941
,
chr10-CpG: 101/Downstream/6985
Upstream sequence
TTATAATGAAATTGATTTGTAGTCTGTTTTGCCGTAAACTTGTTTTTCTTTAAATTGTTCTTACAGTGATATCTTACTATTTTTAACTGTCTGGGGTTTC
Downstream sequence
TGATATGGGGATTTCAGCCCCTGGTTAATCAGTCTTGTCCCTACAAGTCCCTGATGCAGTATGTTTATTTGTGATGTTTAAAGAACATTTCTTggctggg
Target sequence
AACTTGTTTTTCTTTAAATTGTTCTTACAGTGATATCTTACTATTTTTAACTGTCTGGGGTTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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