Basic Information
VIS ID
TVIS30014674
Fusion event
HIV-PIP4K2A integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
22988011/22699082 (Hg38)
End
22988051/22699082 (Hg38)
Orient
+
Location type
Intronic
Target gene
PIP4K2A
miRNAs that regulate target gene
hsa-mir-425-5p ; hsa-mir-122-5p ; hsa-mir-30b-5p ; hsa-mir-101-3p ; hsa-mir-193b-3p ; hsa-mir-4270 ; hsa-mir-4441 ; hsa-mir-6754-5p ; hsa-mir-4684-3p ; hsa-mir-218-5p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-4763-3p ; hsa-mir-4683 ; hsa-mir-1207-5p ; hsa-mir-571 ; hsa-mir-219a-1-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-6760-5p ; hsa-mir-548al ; hsa-mir-4445-3p ; hsa-mir-5701 ; hsa-mir-501-5p ; hsa-mir-500a-5p ; hsa-mir-4668-3p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-548c-3p ; hsa-mir-5687 ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-6515-5p ; hsa-mir-4443 ; hsa-mir-93-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-1265/Upstream/1202441; hsa-mir-107/Downstream/1576603;
Nearest TSS
ENST00000439456/Upstream/7252; ENST00000465729/Downstream/15026;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/220961, chr10-CpG: 91/Downstream/14144
Upstream sequence
TCCTGGCTCAAATATTCATTGGCATGTGTTAAATCTGTGAGTATCCGATGCCAGAACTGCAAGAGAAAGTGAATTAGACAAAAAGATTAGCTTCTCCTAA
Downstream sequence
TACTTTGGCGCAACGTGCCAAAAAGAAAGTGCCTTATGGATTTATCATAATTTCAGAAACAATATCTGTTTCCCAACAGTTCTTCTGATGCCAAAGCATT
Target sequence
CCTATTTTTTTAATGTCCCTAAAATTTGCTCCTGTCCTCC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate