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TVIS30014677
Basic Information
VIS ID
TVIS30014677
Fusion event
HIV-YME1L1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
27428688/27139759 (Hg38)
End
27428536/27139759 (Hg38)
Orient
-
Location type
Intronic
Target gene
YME1L1
miRNAs that regulate target gene
hsa-mir-21-5p
;
hsa-mir-331-3p
;
hsa-mir-374a-5p
;
hsa-mir-5698
;
hsa-mir-143-5p
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-6499-3p
;
hsa-mir-4679
;
hsa-mir-1914-5p
;
hsa-mir-5693
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-342-3p
;
hsa-mir-1228-3p
;
hsa-mir-500a-5p
;
hsa-mir-200a-3p
;
hsa-mir-141-3p
;
hsa-mir-3178
;
hsa-mir-6499-5p
;
hsa-mir-4673
;
hsa-mir-4645-5p
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-3187-3p
;
hsa-mir-4435
;
hsa-mir-588
;
hsa-mir-4701-5p
;
hsa-mir-548s
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-6131
;
hsa-mir-4755-3p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-3663-5p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-4716-5p
;
hsa-mir-4781-3p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-3135b
;
hsa-mir-3664-5p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-6780a-5p
;
hsa-mir-450a-1-3p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-7977
;
hsa-mir-3165
;
hsa-mir-6745
;
hsa-mir-363-5p
;
hsa-mir-6799-5p
;
hsa-mir-6785-5p
;
hsa-mir-6883-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-6804-5p
;
hsa-mir-6089
;
hsa-mir-151b
;
hsa-mir-151a-5p
;
hsa-mir-383-3p
;
hsa-mir-4779
Nearest miRNA
hsa-mir-1265/Upstream/2863978; hsa-mir-107/Downstream/1149499;
Nearest TSS
ENST00000439456/Upstream/3422;
ENST00000477034/Downstream/14467;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/39066
,
chr10-CpG: 30/Downstream/14342
Upstream sequence
TTCATGGTTATTAtcctatctcttcttgggttaactttgttaattaattgcttagacaattgtccatttcaacatatttttatttttgacataaagttac
Downstream sequence
acatactaccttgcaattttaaaaccttcacatatccatggcaattcccactcatacttctaatactgtctgtattttcctgttgtttcttaatcagaat
Target sequence
CTAGTGCCTCTGGGGCAAAGGGACAATATTTTTAAAATACTGTCTTTTAAACTTCATGGTTATTAtcctatctcttcttgggttaactttgttaattaattgcttagacaattgtccatttcaacatatttttatttttgacataaagttac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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