Basic Information
VIS ID
TVIS30014682
Fusion event
HIV-LOC105378275 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
44281353/43785905 (Hg38)
End
44281424/43785905 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
LOC105378275
Nearest miRNA
hsa-mir-1265/Upstream/788224; hsa-mir-107/Downstream/1378109;
Nearest TSS
ENST00000439456/Upstream/7080; ENST00000374432/Downstream/59401;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/57327, chr10-CpG: 24/Downstream/219628
Nearby gene
HNRNPA3P1(No orient, 1506)
Upstream sequence
CTAAGAGCACCCTTGTATGTCAATACCTACTGAAAAGTATCTAACTCTACAGATACCTTAATAGCTAAGCGGGGGACATATGACCCAATTTTGGGTGTTT
Downstream sequence
CTTGTGCCTTTGGCCTCtgtccttcctctgccgtccatcttcttcctcccatcttggcccctggaaatgctgggagcacagcagccatcctgtgatccca
Target sequence
GGATGGAATCAGAAGTCACTAGGGGTGGGGCTTAAAGCAAAAAAATCTTTTTGGTGATCTGACAATGCTCG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate